New drug duo aims to shrink advanced tumors

NCT ID NCT04626635

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This study tests an experimental drug called marlotamig (REGN7075) alone or with cemiplimab (with or without chemo) in people with advanced solid tumors. The goal is to find the safest dose and see if the combination can shrink tumors or slow their growth. About 933 adults with advanced cancer are being recruited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Baskent Universitesi
RECRUITING

Yüreğir, Adana, 01120, Turkey (Türkiye)
Begin Army Instruction Hospital
RECRUITING

Saint-Mandé, Île-de-France Region, 94240, France
Centre Antoine Lacassagne
RECRUITING

Nice, Provence Alpes Cote dAzur, 06189, France
Centre Georges Francois Leclerc
RECRUITING

Dijon, Bourgogne-Franche-Comté, 21034, France
Centre Hospitalier Universitaire (CHU) de Lille
RECRUITING

Lille, Hauts-de-France, 59000, France
Centre Hospitalier Universitaire (CHU) de Poitiers
RECRUITING

Poitiers, New Aquitaine, 86021, France
Centre Jean Perrin
WITHDRAWN

Clermont-Ferrand, Auvergne-Rhône, 63011, France
Centre Leon Berard (CLB) - Centre de Recherche en Cancerologie Lyon-Est (CRCL)
RECRUITING

Lyon, Auvergne-Rhone, 69008, France
Ciftlikkoy Campus Yenisehir Mersin
RECRUITING

Mersin, 33343, Turkey (Türkiye)
Dana Farber Cancer Institute Brookline Avenue
WITHDRAWN

Boston, Massachusetts, 02215, United States
Dom Lekarski SA
RECRUITING

Szczecin, Zach, 70-784, Poland
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi
RECRUITING

Ankara, 06200, Turkey (Türkiye)
Erasmus MC
RECRUITING

Rotterdam, 3015 GD, Netherlands
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
Genesis Care Hospital San Francisco de Asis
RECRUITING

Madrid, 28002, Spain
Gustave Roussy
RECRUITING

Villejuif, Île-de-France Region, 94800, France
Hadassah Medical Center
RECRUITING

Jerusalem, 91220, Israel
Hopital Lyon Sud
RECRUITING

Pierre-Bénite, Auvergne-Rhône, 69310, France
Hospital 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Clinico San Carlos
RECRUITING

Madrid, 28040, Spain
Hospital Clinico Universitario - University of Valencia
RECRUITING

Valencia, 28040, Spain
Hospital General de Catalunya
RECRUITING

Sant Cugat del Vallès, Barcelona, 08195, Spain
Hospital Paris Saint-Joseph
RECRUITING

Paris, 75014, France
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Quiron Salud Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Institut Bergonie
RECRUITING

Bordeaux, New Aquitaine, 33076, France
Institut Claudius Regaud, IUCT-Oncopole
RECRUITING

Toulouse, Haute-Garonne, 31059, France
Istanbul Medeniyet University - Prof Dr Suleyman Yalcin Sehir Hospital
RECRUITING

Istanbul, 81450, Turkey (Türkiye)
Istanbul University Cerrahpasa at Cerrahpasa Medical Faculty
WITHDRAWN

Istanbul, 34450, Turkey (Türkiye)
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Medpolonia Sp. z o.o.
RECRUITING

Poznan, Wielkopolska, 60-693, Poland
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Moffitt Cancer Center
COMPLETED

Tampa, Florida, 33612, United States
Nantes University Hospital
RECRUITING

Nantes, Pays de la Loire Region, 44093, France
Netherlands Cancer Institute
RECRUITING

Amsterdam, 1066 CX, Netherlands
Rambam Health Care Campus
RECRUITING

Haifa, 3109601, Israel
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08901, United States
START Midwest - Cancer & Hematology Centers of Western Michigan, PC
RECRUITING

Grand Rapids, Michigan, 49546, United States
Sarah Cannon Research Institute - 25th Ave
RECRUITING

Nashville, Tennessee, 37203, United States
Shaare Zedek Medical Center
RECRUITING

Jerusalem, 9103102, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5265601, Israel
Soroka University Medical Center
RECRUITING

Beersheba, 84101, Israel
South Texas Oncology And Hematology
COMPLETED

San Antonio, Texas, 78229, United States
Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 64239, Israel
The Regents of the University of California, San Francisco
RECRUITING

San Francisco, California, 94118, United States
The Stefanie Spielman Comprehensive Breast Center
COMPLETED

Columbus, Ohio, 43212, United States
University of California Los Angeles (UCLA) Medical Center
RECRUITING

Los Angeles, California, 90095, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Colorado Hospital - Anschutz Cancer Pavilion - Lung Cancer Clinic
RECRUITING

Aurora, Colorado, 80045, United States
University of Florida Health
RECRUITING

Gainesville, Florida, 32608, United States
University of Illinois Cancer Center
RECRUITING

Chicago, Illinois, 60612, United States
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Washington/Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Valkyrie Clinical Trials
RECRUITING

Los Angeles, California, 90067, United States
Vanderbilt Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMORS ADVANCED SOLID TUMORS