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New drug duo takes on hard-to-treat lymphoma

NCT ID NCT05685173

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Mar 31, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This early-stage study tests a new drug (REGN5837) combined with another drug (odronextamab) in about 107 people whose aggressive B-cell lymphoma has not responded to at least two prior treatments. The first part finds a safe dose; the second part checks how well the combination works. Researchers will also monitor side effects and drug levels in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam University Medical Centre, location AMC

    RECRUITING

    Amsterdam, 1100AZ, Netherlands

  • CHU de Bordeaux

    RECRUITING

    Talence, New Aquitaine, 33404, France

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Erasmus Medical Center Rotterdam

    RECRUITING

    Rotterdam, South Holland, 3015, Netherlands

  • Gustave Roussy

    RECRUITING

    Villejuif, Île-de-France Region, 94800, France

  • Harvard Medical School - Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Hopital Saint Louis

    RECRUITING

    Paris, 75010, France

  • Hospital Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • NYU Langone Health Perlmutter Cancer Center

    RECRUITING

    New York, New York, 10016, United States

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40207, United States

  • Royal Cornwall Hospitals NHS Trust

    RECRUITING

    Truro, Cornwall, TR1 3LJ, United Kingdom

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • Southampton General Hospital

    RECRUITING

    Southampton, Hampshire, SO16 6YD, United Kingdom

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • UT Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

  • University Hospital and Research Institute

    RECRUITING

    Madrid, 28041, Spain

  • University of California Los Angeles (UCLA) Medical Center

    RECRUITING

    Santa Monica, California, 90404, United States

  • Western General Hospital

    RECRUITING

    Edinburgh, Scotland, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.

B-CELL NON-HODGKINS LYMPHOMA (B-NHL) B-CELL NON-HODGKINS LYMPHOMA (B-NHL)