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New combo therapy aims to control Hard-to-Treat blood cancer

NCT ID NCT05137054

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times

Summary

This early-stage study tests an experimental drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has come back after prior therapy. The main goal is to see if these combinations are safe and to find the right doses. About 317 participants will be enrolled, and researchers will also check how well the drugs work and what side effects occur.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Montpellier - Departement D'Hematologie

    RECRUITING

    Montpellier, 34295, France

  • CHU de Lille - Rue Michel Polonovski

    SUSPENDED

    Lille, Nord, 59037, France

  • Centre Hospitalier Universitaire (CHU) de Poitiers

    RECRUITING

    Poitiers, New Aquitaine, 86021, France

  • Centre Hospitalier Universitaire Angers

    RECRUITING

    Angers, 49933, France

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Clinica Universidad de Navarra - Madrid

    RECRUITING

    Madrid, 28027, Spain

  • Dana Farber/Harvard Cancer Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Evangelismos General Hospital

    RECRUITING

    Athens, Attica, 10676, Greece

  • General Hospital of Athens Alexandra

    RECRUITING

    Athens, 11528, Greece

  • Hadassah Medical Center

    RECRUITING

    Jerusalem, 91120, Israel

  • Hopital Necker

    RECRUITING

    Paris, Île-de-France Region, 75015, France

  • Hospital Clinic de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Clinico Universitario de Santiago

    RECRUITING

    Santiago de Compostela, A Coruna, 15706, Spain

  • Hospital Germans Trias i Pujol

    RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Hospital Henri Mondor

    RECRUITING

    Créteil, Île-de-France Region, 94000, France

  • Hospital Universitario HM Sanchinarro

    RECRUITING

    Madrid, 28050, Spain

  • Hospital Universitario Marques de Valdecilla

    RECRUITING

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Quiron Salud Madrid

    RECRUITING

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario Ramon y Cajal - Servicio de Psiquiatria

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Indiana University Health Simon Cancer Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Institut Catala d'Oncologia (ICO) - Hospital Duran i Reynals,

    RECRUITING

    Barcelona, 08908, Spain

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Nantes University Hospital

    RECRUITING

    Nantes, Pays de la Loire Region, 44093, France

  • New York Presbyterian Hospital Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Rambam Health Care Campus

    RECRUITING

    Haifa, 3109601, Israel

  • Saint Antoine Hospital

    RECRUITING

    Paris, 75571, France

  • Saint Louis Hospital

    RECRUITING

    Paris, Île-de-France Region, 75010, France

  • Scripps Clinic Torrey Pines

    RECRUITING

    La Jolla, California, 92037, United States

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, Central District, 5265601, Israel

  • The Ohio State University James Cancer Hospital

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Universitaru Hospital La Princesa

    RECRUITING

    Madrid, 28006, Spain

  • University Hospital and Research Institute

    RECRUITING

    Madrid, 28041, Spain

  • University Hospital of Salamanca

    RECRUITING

    Salamanca, 37007, Spain

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

  • VA Puget Sound Health Care System

    RECRUITING

    Seattle, Washington, 98108, United States

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Weill Cornell Medicine/New York Presbyterian Hospital

    RECRUITING

    New York, New York, 10021, United States

  • Winship Cancer Institute of Emory University

    RECRUITING

    Atlanta, Georgia, 30004, United States

Conditions

Explore the condition pages connected to this study.

MULTIPLE MYELOMA