New tablet tool aims to ease emotional burden for ICU Decision-Makers

NCT ID NCT07630844

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests REFRAME, a short tablet-based program designed to help family members manage overwhelming emotions when making medical decisions for critically ill loved ones in the ICU. About 387 participants will be randomly assigned to either REFRAME or an informational support program. The goal is to see if REFRAME reduces depressive symptoms and improves emotional regulation, potentially leading to a widely available tool for families in crisis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

REFRAME (a tablet-based emotion regulation program)

What this could lead to

If it works, this could provide a simple, widely accessible tool to reduce emotional suffering and improve medical decision-making for families in crisis.

What could go wrong

This is an early-stage behavioral trial with no drug involved, so the effect may be small or not generalizable. Results depend on participants' engagement and may not apply to all settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Critical Illness Emotional Regulation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••