Peer program fights stigma to boost HIV prevention in brazil

NCT ID NCT04114955

Completed Prevention Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a program called Manas por Manas to help transgender women in São Paulo, Brazil, overcome stigma and access HIV testing and PrEP (a daily pill that prevents HIV). The program included group sessions led by peers and one-on-one support. Researchers compared HIV testing and PrEP use between women who received the program and those who did not. The goal was to see if reducing stigma leads to better prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: peer-led behavioral intervention (Manas por Manas)
What this could lead to: If successful, this approach could help reduce HIV infections among transgender women by making it easier to access testing and prevention pills.
What could go wrong: This is a completed trial, but results may not apply to other groups or regions. The intervention relies on peer support, which may not work everywhere.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV PREVENTION

Contacts and locations

Locations

CRT - Centro de Referência e Treinamento DST/AIDS

São Paulo, Brazil
SAE - Serviço de Assistência Especializada Campos Elíseos

São Paulo, Brazil

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