Could less radiation plus a vitamin a drug beat head and neck cancer?

NCT ID NCT06706401

First seen Nov 18, 2025 · Last updated May 12, 2026 · Updated 21 times

Summary

This study tests two ideas for people with certain head and neck cancers: using a smaller radiation area to reduce side effects, and adding a drug called ATRA (a form of vitamin A) to help control the disease. About 460 adults will be randomly assigned to standard or smaller radiation, with or without ATRA. The goal is to see if these approaches can keep cancer from coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP - Hôpital Tenon

    RECRUITING

    Paris, 75020, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, 06189, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Léon Bérard

    RECRUITING

    Lyon, France, 69008, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut Godinot

    RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, France, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de Cancérologie de Lorraine

    RECRUITING

    Vandœuvre-lès-Nancy, France, 54519, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de Cancérologie de l'Ouest - Paul Papin

    RECRUITING

    Angers, 49055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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