Can we safely use less blood for leukemia patients?
NCT ID NCT06710418
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times
Summary
This study looks at whether giving blood transfusions only when hemoglobin drops below 7 gm/dL (instead of 9 gm/dL) is safe and maintains quality of life in leukemia patients after chemotherapy or stem cell transplant. About 50 adults with certain blood cancers will be randomly assigned to one of two transfusion thresholds. The goal is to see if the lower threshold is feasible and doesn't cause more bleeding or worse quality of life, which could help conserve blood supplies.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fred Hutch/University of Washington Cancer Consortium
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Packed red blood cell transfusion
What this could lead to
If successful, this could show that using a lower hemoglobin threshold for transfusions is safe and effective, helping conserve blood supplies and reduce side effects.
What could go wrong
This is a small, early feasibility study with only 50 participants, so results may not apply broadly. The restrictive threshold might not maintain quality of life as well as the liberal one.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.