Can we safely use less blood for leukemia patients?

NCT ID NCT06710418

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether giving blood transfusions only when hemoglobin drops below 7 gm/dL (instead of 9 gm/dL) is safe and maintains quality of life in leukemia patients after chemotherapy or stem cell transplant. About 50 adults with certain blood cancers will be randomly assigned to one of two transfusion thresholds. The goal is to see if the lower threshold is feasible and doesn't cause more bleeding or worse quality of life, which could help conserve blood supplies.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Packed red blood cell transfusion
What this could lead to
If successful, this could show that using a lower hemoglobin threshold for transfusions is safe and effective, helping conserve blood supplies and reduce side effects.
What could go wrong
This is a small, early feasibility study with only 50 participants, so results may not apply broadly. The restrictive threshold might not maintain quality of life as well as the liberal one.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

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Other studies related to the condition(s) this trial covers.