New combo therapy aims to boost organ preservation in aggressive rectal cancer
NCT ID NCT07551479
First seen May 01, 2026 · Last updated May 01, 2026
Summary
This phase 3 trial tests whether a shorter course of radiation followed by chemotherapy and an immunotherapy drug (Serplulimab) works better than the standard long-course chemoradiation for people with high-risk locally advanced rectal cancer. About 612 adults with specific high-risk features will be randomly assigned to one of two treatment plans. The goal is to see which approach leads to better 3-year survival without cancer events and possibly allows more patients to avoid surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fudan University Shanghai Cancer Center
Shanghai, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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