New combo therapy aims to wipe out rectal cancer without surgery

NCT ID NCT06577194

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 33 times

Summary

This study tests a new treatment plan for people with locally advanced rectal cancer. Participants first get a short course of radiation along with an immune-boosting drug (IL-2). Then they receive chemotherapy (CAPOX) plus two immunotherapy drugs (a PD-1 antibody and IL-2). The goal is to see if this combination can make the cancer completely disappear. The study enrolls 35 adults aged 18-70 with good overall health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jiangsu Province Hospital

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.