New combo aims to shrink tough rectal tumors before surgery

NCT ID NCT01941641

First seen Nov 17, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This study tested a powerful chemotherapy combination (FOLFOXIRI) followed by chemoradiation before surgery in 40 people with high-risk rectal cancer. The goal was to shrink tumors enough to allow complete removal. Researchers measured how well the tumors responded and tracked side effects and long-term outcomes like survival and recurrence.

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Contacts and locations

Locations

  • Department of Clinical Oncology

    Hong Kong, Hong Kong

Conditions

Explore the condition pages connected to this study.