New drug combo tested to shrink rectal tumors before surgery

NCT ID NCT03516708

Summary

This study is testing if adding an experimental drug called epacadostat to the standard pre-surgery treatment (chemotherapy and radiation) works better for people with locally advanced rectal cancer. The main goals are to find the safest dose of the new combination and to see if it helps shrink tumors more effectively before surgery. About 49 adults with newly diagnosed rectal cancer that hasn't spread are being recruited.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Henry Ford Cancer Institute

    WITHDRAWN

    Detroit, Michigan, 48202, United States

  • University of California Irvine - Chao Family Comprehensive Cancer Center

    WITHDRAWN

    Orange, California, 92868, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

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Conditions

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