New combo therapy aims to wipe out rectal cancer before surgery
NCT ID NCT07281768
First seen Jan 07, 2026 · Last updated May 16, 2026 · Updated 21 times
Summary
This study tests whether adding immunotherapy drugs (cemiplimab alone or with fianlimab or REGN7075) to standard chemotherapy can improve outcomes for people with locally advanced rectal cancer before they have surgery. About 66 adults with a specific type of rectal cancer (MSS) that hasn't spread will receive the drug combination, then have surgery to see if the cancer is completely gone. The main goal is to see how many patients have no cancer cells left in the removed tissue.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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