Immunotherapy boost may help rectal cancer patients avoid surgery

NCT ID NCT06312982

First seen Jan 13, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study tests whether adding the immunotherapy drug tislelizumab to standard chemoradiation can improve outcomes for people with locally advanced rectal cancer. About 375 adults will receive either chemoradiation alone or combined with tislelizumab before surgery. The goal is to see if the combination leads to more complete tumor responses and helps more patients keep their rectum.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100050, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Friendship Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100050, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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