New talk therapy aims to boost recovery in Treatment-Resistant mental illness

NCT ID NCT07047651

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a new recovery-focused psychotherapy program (RECOVERYTRSGR or RECOVERYTRSBDGR) to standard medication can improve thinking, symptoms, and daily function in people with treatment-resistant schizophrenia or bipolar disorder. About 84 adults aged 18–65 will take part. The program involves up to 190 therapy sessions, and researchers will measure changes in memory, problem-solving, mood, and overall recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

combination of antipsychotic, anxiolytic, and antidepressant medications plus recovery-oriented psychotherapy (RECOVERYTRSGR or RECOVERYTRSBDGR)

What this could lead to

If it works, this could point toward a better way to manage treatment-resistant schizophrenia and bipolar disorder, improving thinking, symptoms, and daily life.

What could go wrong

This is a small Phase 4 study with only 84 participants, so results may not apply to everyone. The intensive 190-session program may be hard to complete, and benefits may not be large or lasting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bipolar disorder Schizophrenia, Treatment-Resistant treatment-refractory schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Private practice of Dr. S. Rakitzi and Dr. P. Georgila ILISION 34 15771 ATHENS GREECE

    Athens, 15771, Greece