Sound waves aimed at brain may quiet schizophrenia symptoms
NCT ID NCT05259306
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This pilot study tests whether low-intensity focused ultrasound, guided by MRI, can safely and feasibly target a deep brain region (the thalamus) in people with treatment-resistant schizophrenia. Only 3 participants were planned, and the study is currently suspended. The goal is to see if the procedure is practical and to measure any changes in symptoms like hallucinations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI-guided low-intensity focused ultrasound (LIFU) device
What this could lead to
If it works, this could point toward a new way to ease symptoms of treatment-resistant schizophrenia without surgery or medication.
What could go wrong
This is a very early pilot study with only 3 participants and is currently suspended. It tests feasibility, not effectiveness, so results may not lead to a treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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NYU Langone Health
New York, New York, 10016, United States