Could rebreathing CO2 zap long COVID brain fog? new trial aims to find out

NCT ID NCT06928506

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study is testing a device called Hi-OxSR that lets people briefly rebreathe carbon dioxide (CO2) to see if it can reduce brain fog and fatigue caused by Long COVID. The researchers believe CO2 may calm the immune system and reduce inflammation. About 120 adults with lingering COVID symptoms will use the device at home for 14 days, and their thinking speed and memory will be measured with online tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Universitaire de Sherbrooke

    NOT_YET_RECRUITING

    Sherbrooke, Quebec, Canada

    Contact Email: •••••@•••••

  • Kaye Edmonton Clinic

    NOT_YET_RECRUITING

    Edmonton, Alberta, Canada

    Contact Email: •••••@•••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.