Knee surgery pain study: could rebound pain predict months of suffering?
NCT ID NCT07511985
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study will follow 220 adults having knee replacement surgery to see if a short burst of pain after a nerve block (called rebound pain) is linked to chronic pain that lasts for months. Participants will keep pain diaries and answer surveys at 3 and 6 months after surgery. No new treatments are being tested—the goal is simply to understand the connection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors predict and prevent chronic pain after knee replacement by managing rebound pain better.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks for a link, so it won't prove that preventing rebound pain stops chronic pain. Results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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