Knee surgery pain study: could rebound pain predict months of suffering?

NCT ID NCT07511985

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will follow 220 adults having knee replacement surgery to see if a short burst of pain after a nerve block (called rebound pain) is linked to chronic pain that lasts for months. Participants will keep pain diaries and answer surveys at 3 and 6 months after surgery. No new treatments are being tested—the goal is simply to understand the connection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors predict and prevent chronic pain after knee replacement by managing rebound pain better.

What could go wrong

This is an observational study, not a treatment trial. It only looks for a link, so it won't prove that preventing rebound pain stops chronic pain. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••