Anti-Ulcer drug shows promise for arthritis relief
NCT ID NCT05166304
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether rebamipide, a drug normally used for stomach ulcers, can help control rheumatoid arthritis when added to standard methotrexate therapy. Sixty adults with active arthritis took either rebamipide or a placebo three times daily. Researchers measured joint pain, swelling, and disability to see if the drug improves symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rebamipide (an anti-ulcer drug) taken as 100 mg tablets three times daily
What this could lead to
If it works, this could offer a new, affordable add-on treatment to better control rheumatoid arthritis symptoms.
What could go wrong
This is a small, early-phase trial (Phase 1/2) with only 60 participants, so results may not apply broadly. Rebamipide is not a standard arthritis drug, and its benefits are uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Minia University
Minya, Egypt