New combo offers hope for kids with Tough-to-Treat leukemia

NCT ID NCT05192889

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 35 times

Summary

This study tests two drugs, venetoclax and navitoclax, combined with other treatments for children whose acute lymphoblastic leukemia has returned or not responded to standard therapy. The goal is to see if this combination can clear the leukemia from the bone marrow more effectively than past treatments. About 35 children and young adults will take part at St. Jude Children's Research Hospital.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.