New drug duo targets hard-to-treat cancers with RAS mutations
NCT ID NCT07397338
First seen Feb 15, 2026 · Last updated Apr 30, 2026 · Updated 9 times
Summary
This study tests whether combining two experimental drugs (RAS(ON) inhibitors and ivonescimab) is safe and can shrink tumors in adults with advanced solid cancers that have a RAS mutation. About 370 people with lung, colorectal, or other solid tumors that have worsened after standard treatment will take part. The goal is to control the disease, not cure it.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Eastern Connecticut Hematology and Oncology Associates
RECRUITINGNorwich, Connecticut, 06360, United States
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NEXT Dallas
RECRUITINGIrving, Texas, 75039, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tennessee Oncology
RECRUITINGNashville, Tennessee, 37023, United States
Conditions
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