New drug duo targets Hard-to-Treat rare cancers

NCT ID NCT05142241

Summary

This study is testing whether a combination of two oral drugs, talazoparib and temozolomide, can shrink advanced rare cancers that have spread and for which standard treatments have stopped working. The trial aims to see if this drug pair can stop tumor growth by damaging cancer cell DNA and preventing its repair. It is for adults and some adolescents with specific rare solid tumors who have no other standard treatment options available.

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Contacts and locations

Locations

  • National Cancer Institute Developmental Therapeutics Clinic

    Bethesda, Maryland, 20892, United States

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.