Blood test could replace painful biopsies for cancer patients

NCT ID NCT05057234

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a blood test (liquid biopsy) can find cancer mutations as well as the standard tissue biopsy. Researchers will compare the two methods in 1,500 advanced cancer patients to see if the blood test helps doctors choose better treatments and saves money. The goal is to make precision medicine easier and less invasive for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FoundationOne liquid CDx (a blood test that looks for cancer DNA)

What this could lead to

If successful, this could show that a simple blood test can replace or supplement tissue biopsies, making precision cancer treatment faster and more accessible.

What could go wrong

This is an observational study, not a treatment trial. It compares two testing methods, so it won't directly improve outcomes. The blood test may miss some mutations found in tissue, and results may not apply to all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer metastatic melanoma metastatic prostate carcinoma neoplasm non-small cell lung carcinoma ovarian cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BC Cancer

    Vancouver, British Columbia, V5Z4E6, Canada