New hope for kids with tough cancer: testing drug combo for relapsed tumors
NCT ID NCT04145349
Summary
This study is testing whether adding the drug ramucirumab to standard chemotherapy can help control a rare and aggressive cancer called desmoplastic small round cell tumor (DSRCT) in children and young adults whose cancer has returned or stopped responding to previous treatments. The trial aims to see if this combination is safe and can slow or stop tumor growth. Participation could last 12 months or longer depending on how the cancer responds.
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Contacts and locations
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Locations
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Azienda Ospedaliera di Padova
Padua, Veneto, 35128, Italy
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia (CHOP)
Philadelphia, Pennsylvania, 19104, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, 20133, Italy
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Hospital Universitari Vall d'Hebron
Barcelona, Barcelona [Barcelona], 08035, Spain
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Hospital Universitario Virgen Del Rocio
Seville, 41013, Spain
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Humanitas
Rozzano, Milano, 20089, Italy
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Kyushu University Hospital
Fukuoka, 812-8582, Japan
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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Ospedale Pediatrico Bambino Gesù
Rome, Roma, 165, Italy
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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Royal Children's Hospital
Parkville, Victoria, 3052, Australia
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Royal Manchester Children's Hospital
Manchester, M13 9WL, United Kingdom
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Royal Marsden Hospital (Sutton)
London, Sutton, SM2 5PT, United Kingdom
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The Christie
Manchester, M20 4BX, United Kingdom
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Universitaetsklinikum Essen
Essen, North Rhine-Westphalia, 45122, Germany
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Universitaetsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Universitaetsklinikum Hamburg-Eppendorf
Hamburg, 20251, Germany
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University College London Hospital
London, London, City of, NW1 2PG, United Kingdom
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Washington University
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.