Gene test could personalize breast cancer prevention drug

NCT ID NCT06062810

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines how genetic variations (SNPs) in certain genes influence how well the drug raloxifene works and its side effects in 600 patients with lobular carcinoma in situ (LCIS), a high-risk breast condition. Participants take raloxifene daily, and researchers sequence their DNA to find links between genes and treatment outcomes. The goal is to make raloxifene therapy more personalized and safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Raloxifene

What this could lead to

If successful, this could help doctors predict which patients will benefit most from raloxifene and who might experience side effects, leading to more personalized treatment.

What could go wrong

This is an early-stage genetic analysis, not a test of a new drug. The findings may not change current practice or may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm lobular breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medicine Invention Design, Inc. - IORG0007849 - NPI 1023387701

    Rockville, Maryland, 20853, United States