New combo therapy shows promise for Tough-to-Treat prostate cancer

NCT ID NCT02225704

First seen Apr 14, 2026 · Last updated Apr 29, 2026 · Updated 3 times

Summary

This study tested whether combining two drugs, Radium-223 and enzalutamide, is safe for men with advanced prostate cancer that has spread to other parts of the body and no longer responds to standard hormone therapy. 45 men participated. The goal was to see how many experienced serious side effects and how long the treatment kept the cancer from getting worse.

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Contacts and locations

Locations

  • Cork University Hospital

    Cork, Ireland

  • Galway University Hospital

    Galway, Ireland

  • Mater Misericordiae University Hospital

    Dublin, Ireland

  • Mater Private Hospital

    Dublin, Ireland

  • SLRON, St James's Hospital

    Dublin, Ireland

  • St Vincents University Hospital / AMNCH

    Dublin, Ireland

  • Tallaght Hospital

    Dublin, Ireland

Conditions

Explore the condition pages connected to this study.