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Newer radiation technique may spare bladder and bowel in endometrial cancer patients

NCT ID NCT01164150

Terminated Symptom relief Sponsor: Cancer Trials Ireland Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compared two ways of giving pelvic radiotherapy after surgery for endometrial cancer: standard 3D planning versus a newer technique called IMRT. The goal was to see if IMRT could reduce side effects like bladder and bowel problems. The study enrolled 92 participants but was stopped early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy (IMRT vs 3D planned)
What this could lead to
If successful, this could show that IMRT reduces short-term bowel and bladder side effects compared to standard 3D radiotherapy for endometrial cancer patients.
What could go wrong
This is a small, early-phase trial that was terminated early, so results may be limited. It does not test survival or cancer control, only side effect reduction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial mixed adenocarcinoma endometrial serous adenocarcinoma endometrium adenocarcinoma endometrium neoplasm radiation injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER GASTROINTESTINAL COMPLICATIONS RADIATION TOXICITY URINARY COMPLICATIONS

Contacts and locations

Locations

  • Mid-Western Radiation Oncology Centre

    Limerick, Ireland

  • St Luke's Centre for Radiation Oncology at Beaumont Hospital

    Dublin, Ireland

  • St Luke's Centre for Radiation Oncology at St James Hospital

    Dublin, Ireland

  • St Luke's Centre for Radiation Oncology at St Lukes Hospital

    Dublin, Ireland

  • St Luke's Radiation Oncology Network (SLRON) Centres

    Dublin, 6, Ireland

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