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Should you zap or wait? new trial tackles meningioma dilemma

NCT ID NCT03180268

Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

This phase III trial compares radiation therapy to simple observation in patients who have had a grade II meningioma completely removed by surgery. The goal is to see if radiation helps keep the tumor from coming back. About 163 participants will be randomly assigned to either receive intensity-modulated radiation therapy or undergo observation with regular MRI scans. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
radiation therapy (intensity-modulated radiation therapy, IMRT)
What this could lead to
If radiation works better than observation, this could become the standard approach to prevent tumor regrowth after surgery for grade II meningioma.
What could go wrong
This is a mid-stage trial with 163 participants, so results may not apply to everyone. Radiation has side effects, and it's possible that observation alone is just as good, meaning some patients would get unnecessary treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 163 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2017

Expected to finish

Jun 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * PRIOR TO STEP 1 REGISTRATION: * The patient must have a newly diagnosed unifocal intracranial meningioma, gross totally resected, and histologically confirmed as WHO grade II based upon pathology findings at the enrolling institution. WHO grade will be assigned according to WHO 2016 criteria * Gross total resection (GTR) will be interpreted as modified Simpson grade 1-3 without gross residual dural-based or extradural tumor. GTR must be confirmed both by modified Simpson grade and by post-operative magnetic resonance imaging (MRI) findings. The modified Simpson grade can be inferred from the operative report (surgeon does not need to explicitly describe the Simpson grade for the purposes of eligibility) * Step 1 registration must occur within 180 days of the initial surgery; this will provide sufficient time for post-operative imaging confirmation of resection extent after resolution of operative changes. Moreover, it will permit additional surgery if needed to achieve a GTR. Within this 180 day interval, a second surgery is permitted in order to achieve GTR, but even with a second surgery, Step 1 registration must occur within 180 days of the initial resection * GTR must be confirmed on post-operative imaging following the most recent surgery. For protocol enrollment, the assessment of GTR will be made at each site. However, submission of both pre-operative and post-operative MRIs is required for patients. If a second surgery is performed, submission of post-operative MRI is required and pre-operative MRI is required only if obtained. All sequences obtained in the pre- and post-operative MR imaging are to be submitted to National Radiology Group (NRG) Oncology for study registration. The post-operative MRI must be completed within sufficient time to permit step 1 registration within 180 days of the initial resection. These same conditions apply in the setting of a second surgical procedure, although if a second surgery is completed, step 1 registration must still occur with 180 days of initial surgery. Computed tomography (CT) imaging is not required, but may be obtained if desired clinically, for instance to assess calcifications or hyperostosis * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry * NOTE: Central pathology review must occur between steps 1 and 2 of registration. Once appropriate pathology specimens are received, central pathology review will occur within 10 business days, and must confirm WHO grade II meningioma before the patient can proceed to step 2 registration and randomization * PRIOR TO STEP 2 REGISTRATION: * Histologically confirmed diagnosis of WHO grade II meningioma confirmed by central pathology review prior to step 2 registration * Age \>= 18 * History/physical examination, including neurologic examination within 60 days prior to step 2 registration * Post-operative Zubrod performance status 0-1 within 60 days prior to step 2 registration * If the patient is a woman is of childbearing potential, a serum pregnancy test, obtained within 14 days prior to step 2 registration, must be negative, and, if randomized to receive radiation therapy, the woman must agree to use contraception Exclusion Criteria: * Optic nerve sheath meningioma, spinal or other extracranial meningioma, multiple meningiomas, hemangiopericytoma * Definitive evidence of metastatic meningioma (metastasis, although rare, can occur and is exclusionary) * Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years (carcinoma in situ of the breast, oral cavity, cervix, melanoma in situ, or other non-invasive malignancies are permissible) * Previous radiotherapy to the scalp, cranium, brain, or skull base and radiation-induced meningiomas * Major medical illnesses or psychiatric impairments, which in the investigators opinion, will prevent administration or completion of the protocol therapy and/or preclude informed consent; these include, but are not restricted to: * Unstable angina and/or congestive heart failure requiring hospitalization at the time of step 2 registration * Transmural myocardial infarction within the last 6 months prior to step 2 registration * Acute bacterial or fungal infection requiring intravenous antibiotics at the time of step 2 registration * Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of step 2 registration * Type II neurofibromatosis (NF2) * Ailments entailing substantial increases in sensitivity and side effect risk from radiation therapy (ataxia telangiectasia, Nijmegen breakage syndrome, and human immunodeficiency virus (HIV) with CD4 count \< 200 cells/microliter); HIV testing is not required for eligibility for this protocol, and known HIV positive patients are eligible, provided they are under treatment with highly active antiretroviral therapy (HAART) and have a CD4 count \>= 200 cells/microliter within 30 days prior to step 2 registration * Inability to undergo MRI with and without contrast (e.g. claustrophobia, non-MRI compatible implant or foreign body, gadolinium allergy or renal dysfunction preventing the patient from receiving gadolinium- institutional guidelines should be used to determine if patients are at risk for renal dysfunction). Note that patients with severe claustrophobia are permitted on this study if they are willing and able to undergo MRI with adequate sedation or anesthesia

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Conditions

The condition(s) this trial relates to.

grade II meningioma intracranial meningioma meningioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Grade 2 meningioma Intracranial meningioma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    150 sites in 5 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Abbott-Northwestern Hospital

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

  • AdventHealth East Orlando

    SUSPENDED

    Orlando, Florida, 32822, United States

  • AdventHealth Orlando

    SUSPENDED

    Orlando, Florida, 32803, United States

  • Allan Blair Cancer Centre

    ACTIVE_NOT_RECRUITING

    Regina, Saskatchewan, S4T 7T1, Canada

  • American Fork Hospital / Huntsman Intermountain Cancer Center

    RECRUITING

    American Fork, Utah, 84003, United States

    Contact Email: •••••@•••••

  • Arthur J E Child Comprehensive Cancer Centre

    SUSPENDED

    Calgary, Alberta, T2N 5G2, Canada

  • Aspirus Cancer Care - Stevens Point

    RECRUITING

    Stevens Point, Wisconsin, 54481, United States

  • Aspirus Cancer Care - Wisconsin Rapids

    RECRUITING

    Wisconsin Rapids, Wisconsin, 54494, United States

  • Aspirus Regional Cancer Center

    RECRUITING

    Wausau, Wisconsin, 54401, United States

  • Banner University Medical Center - Tucson

    SUSPENDED

    Tucson, Arizona, 85719, United States

  • Baptist MD Anderson Cancer Center

    ACTIVE_NOT_RECRUITING

    Jacksonville, Florida, 32207, United States

  • Beebe Health Campus

    ACTIVE_NOT_RECRUITING

    Rehoboth Beach, Delaware, 19971, United States

  • Benefis Sletten Cancer Institute

    RECRUITING

    Great Falls, Montana, 59405, United States

    Contact Email: •••••@•••••

  • Billings Clinic Cancer Center

    SUSPENDED

    Billings, Montana, 59101, United States

  • Boca Raton Regional Hospital

    ACTIVE_NOT_RECRUITING

    Boca Raton, Florida, 33486, United States

  • CHUM - Centre Hospitalier de l'Universite de Montreal

    SUSPENDED

    Montreal, Quebec, H2X 3E4, Canada

  • California Pacific Medical Center-Pacific Campus

    RECRUITING

    San Francisco, California, 94115, United States

    Contact Email: •••••@•••••

  • Capital Health Medical Center-Hopewell

    RECRUITING

    Pennington, New Jersey, 08534, United States

    Contact Email: •••••@•••••

  • Case Western Reserve University

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

  • Chelsea Hospital

    SUSPENDED

    Chelsea, Michigan, 48118, United States

  • Christiana Care Health System-Christiana Hospital

    ACTIVE_NOT_RECRUITING

    Newark, Delaware, 19718, United States

  • Christiana Care Health System-Concord Health Center

    ACTIVE_NOT_RECRUITING

    Chadds Ford, Pennsylvania, 19317, United States

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Email: •••••@•••••

  • Cross Cancer Institute

    ACTIVE_NOT_RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

  • Dartmouth Cancer Center - North

    RECRUITING

    Saint Johnsbury, Vermont, 05819, United States

  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

    RECRUITING

    Lebanon, New Hampshire, 03756, United States

  • Decatur Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Decatur, Illinois, 62526, United States

  • Drexel Town Square Health Center

    RECRUITING

    Oak Creek, Wisconsin, 53154, United States

  • Emory Proton Therapy Center

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Emory Saint Joseph's Hospital

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • Emory University Hospital/Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Englewood Hospital and Medical Center

    RECRUITING

    Englewood, New Jersey, 07631, United States

  • Essentia Health Cancer Center

    RECRUITING

    Duluth, Minnesota, 55805, United States

    Contact Email: •••••@•••••

  • Fox Chase Cancer Center

    ACTIVE_NOT_RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

  • Froedtert Menomonee Falls Hospital

    RECRUITING

    Menomonee Falls, Wisconsin, 53051, United States

  • Geisinger Cancer Services-Pottsville

    RECRUITING

    Pottsville, Pennsylvania, 17901, United States

    Contact Email: •••••@•••••

  • Geisinger Medical Center

    RECRUITING

    Danville, Pennsylvania, 17822, United States

    Contact Email: •••••@•••••

  • Geisinger Medical Oncology-Lewisburg

    RECRUITING

    Lewisburg, Pennsylvania, 17837, United States

    Contact Email: •••••@•••••

  • Geisinger Wyoming Valley/Henry Cancer Center

    RECRUITING

    Wilkes-Barre, Pennsylvania, 18711, United States

    Contact Email: •••••@•••••

  • Grady Health System

    RECRUITING

    Atlanta, Georgia, 30303, United States

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

  • Helen F Graham Cancer Center

    ACTIVE_NOT_RECRUITING

    Newark, Delaware, 19713, United States

  • Henry Ford Health Saint John Hospital

    SUSPENDED

    Detroit, Michigan, 48236, United States

  • Henry Ford Health Warren Hospital

    SUSPENDED

    Warren, Michigan, 48093, United States

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Email: •••••@•••••

  • Henry Ford Macomb Hospital-Clinton Township

    RECRUITING

    Clinton Township, Michigan, 48038, United States

    Contact Email: •••••@•••••

  • Henry Ford West Bloomfield Hospital

    RECRUITING

    West Bloomfield, Michigan, 48322, United States

    Contact Email: •••••@•••••

  • Hiroshima University Hospital

    RECRUITING

    Hiroshima, 734-8551, Japan

  • Hokkaido University Hospital

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • IU Health Methodist Hospital

    ACTIVE_NOT_RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Indiana University/Melvin and Bren Simon Cancer Center

    ACTIVE_NOT_RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Intermountain Medical Center

    RECRUITING

    Murray, Utah, 84107, United States

    Contact Email: •••••@•••••

  • Iowa Methodist Medical Center

    RECRUITING

    Des Moines, Iowa, 50309, United States

  • Iwate Medical University Hospital

    SUSPENDED

    Shiwa-gun, Iwate, 028-3695, Japan

  • Jersey Shore Medical Center

    RECRUITING

    Neptune City, New Jersey, 07753, United States

  • Juravinski Cancer Centre at Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

  • Kaiser Permanente Cancer Treatment Center

    RECRUITING

    South San Francisco, California, 94080, United States

  • Kaiser Permanente Dublin

    RECRUITING

    Dublin, California, 94568, United States

  • Kaiser Permanente Los Angeles Medical Center

    RECRUITING

    Los Angeles, California, 90027, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente Medical Center - Santa Clara

    RECRUITING

    Santa Clara, California, 95051, United States

  • Kaiser Permanente Oakland-Broadway

    RECRUITING

    Oakland, California, 94611, United States

  • Kaiser Permanente-Anaheim

    RECRUITING

    Anaheim, California, 92806, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente-Bellflower

    RECRUITING

    Bellflower, California, 90706, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente-Ontario

    RECRUITING

    Ontario, California, 91761, United States

    Contact Email: •••••@•••••

  • Kaiser Permanente-Rancho Cordova Cancer Center

    RECRUITING

    Rancho Cordova, California, 95670, United States

  • Keio University

    RECRUITING

    Shinjuku-ku, Tokyo, 160-8582, Japan

  • Kettering Medical Center

    ACTIVE_NOT_RECRUITING

    Kettering, Ohio, 45429, United States

  • King Faisal Specialist Hospital and Research Centre

    SUSPENDED

    Riyadh, 11211, Saudi Arabia

  • Kyorin University Hospital

    RECRUITING

    Mitaka-shi, Tokyo, 181-8611, Japan

  • LDS Hospital

    RECRUITING

    Salt Lake City, Utah, 84143, United States

    Contact Email: •••••@•••••

  • LSU Health Sciences Center at Shreveport

    ACTIVE_NOT_RECRUITING

    Shreveport, Louisiana, 71103, United States

  • Langlade Hospital and Cancer Center

    RECRUITING

    Antigo, Wisconsin, 54409, United States

  • Lankenau Medical Center

    SUSPENDED

    Wynnewood, Pennsylvania, 19096, United States

  • Legacy Good Samaritan Hospital and Medical Center

    ACTIVE_NOT_RECRUITING

    Portland, Oregon, 97210, United States

  • Legacy Mount Hood Medical Center

    ACTIVE_NOT_RECRUITING

    Gresham, Oregon, 97030, United States

  • Legacy Salmon Creek Hospital

    ACTIVE_NOT_RECRUITING

    Vancouver, Washington, 98686, United States

  • Lewistown Hospital

    RECRUITING

    Lewistown, Pennsylvania, 17044, United States

    Contact Email: •••••@•••••

  • Logan Health Medical Center

    SUSPENDED

    Kalispell, Montana, 59901, United States

  • Logan Regional Hospital

    RECRUITING

    Logan, Utah, 84321, United States

    Contact Email: •••••@•••••

  • London Regional Cancer Program

    SUSPENDED

    London, Ontario, N6A 4L6, Canada

  • Los Angeles General Medical Center

    ACTIVE_NOT_RECRUITING

    Los Angeles, California, 90033, United States

  • Loyola University Medical Center

    RECRUITING

    Maywood, Illinois, 60153, United States

  • MU Health - University Hospital/Ellis Fischel Cancer Center

    ACTIVE_NOT_RECRUITING

    Columbia, Missouri, 65212, United States

  • MaineHealth Cancer Care Center of York County

    RECRUITING

    Sanford, Maine, 04073, United States

  • MaineHealth Coastal Cancer Treatment Center

    RECRUITING

    Bath, Maine, 04530, United States

  • MaineHealth Maine Medical Center - Portland

    RECRUITING

    Portland, Maine, 04102, United States

    Contact Email: •••••@•••••

  • MaineHealth Maine Medical Center- Scarborough

    RECRUITING

    Scarborough, Maine, 04074, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center - Minocqua

    RECRUITING

    Minocqua, Wisconsin, 54548, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center - Weston

    RECRUITING

    Weston, Wisconsin, 54476, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center-EC Cancer Center

    RECRUITING

    Eau Claire, Wisconsin, 54701, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center-Marshfield

    RECRUITING

    Marshfield, Wisconsin, 54449, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center-Rice Lake

    RECRUITING

    Rice Lake, Wisconsin, 54868, United States

    Contact Email: •••••@•••••

  • Marshfield Medical Center-River Region at Stevens Point

    RECRUITING

    Stevens Point, Wisconsin, 54482, United States

    Contact Email: •••••@•••••

  • Maryland Proton Treatment Center

    ACTIVE_NOT_RECRUITING

    Baltimore, Maryland, 21201, United States

  • Mayo Clinic Hospital in Arizona

    ACTIVE_NOT_RECRUITING

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic in Arizona

    ACTIVE_NOT_RECRUITING

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • McKay-Dee Hospital Center

    RECRUITING

    Ogden, Utah, 84403, United States

    Contact Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Medical University of South Carolina

    ACTIVE_NOT_RECRUITING

    Charleston, South Carolina, 29425, United States

  • Memorial Hospital West

    RECRUITING

    Pembroke Pines, Florida, 33028, United States

  • Memorial Medical Center

    RECRUITING

    Modesto, California, 95355, United States

    Contact Email: •••••@•••••

  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital

    RECRUITING

    Hollywood, Florida, 33021, United States

  • Memorial Sloan Kettering Basking Ridge

    ACTIVE_NOT_RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    ACTIVE_NOT_RECRUITING

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    ACTIVE_NOT_RECRUITING

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    ACTIVE_NOT_RECRUITING

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    ACTIVE_NOT_RECRUITING

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    ACTIVE_NOT_RECRUITING

    Harrison, New York, 10604, United States

  • Mercy Cancer Center-Elyria

    SUSPENDED

    Elyria, Ohio, 44035, United States

  • Miami Cancer Institute

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33176, United States

  • Miller-Dwan Hospital

    RECRUITING

    Duluth, Minnesota, 55805, United States

    Contact Email: •••••@•••••

  • Moffitt Cancer Center

    SUSPENDED

    Tampa, Florida, 33612, United States

  • MyMichigan Medical Center Saginaw

    SUSPENDED

    Saginaw, Michigan, 48601, United States

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10032, United States

  • NYP/Weill Cornell Medical Center

    SUSPENDED

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    RECRUITING

    Tokyo, 104 0045, Japan

  • New York-Presbyterian/Brooklyn Methodist Hospital

    RECRUITING

    Brooklyn, New York, 11215, United States

  • NorthShore University HealthSystem-Evanston Hospital

    RECRUITING

    Evanston, Illinois, 60201, United States

  • NorthShore University HealthSystem-Glenbrook Hospital

    RECRUITING

    Glenview, Illinois, 60026, United States

  • NorthShore University HealthSystem-Highland Park Hospital

    RECRUITING

    Highland Park, Illinois, 60035, United States

  • Northside Hospital

    ACTIVE_NOT_RECRUITING

    Atlanta, Georgia, 30342, United States

  • Northside Hospital-Forsyth

    ACTIVE_NOT_RECRUITING

    Cumming, Georgia, 30041, United States

  • Northwestern Medicine Cancer Center Delnor

    RECRUITING

    Geneva, Illinois, 60134, United States

  • Northwestern Medicine Cancer Center Warrenville

    RECRUITING

    Warrenville, Illinois, 60555, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Email: •••••@•••••

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Park Nicollet Clinic - Saint Louis Park

    RECRUITING

    Saint Louis Park, Minnesota, 55416, United States

  • Piedmont Fayette Hospital

    RECRUITING

    Fayetteville, Georgia, 30214, United States

  • Piedmont Henry Hospital

    RECRUITING

    Stockbridge, Georgia, 30281, United States

  • Piedmont Hospital

    RECRUITING

    Atlanta, Georgia, 30309, United States

  • Piedmont Newnan Hospital

    RECRUITING

    Newnan, Georgia, 30265, United States

  • Prisma Health Cancer Institute - Eastside

    ACTIVE_NOT_RECRUITING

    Greenville, South Carolina, 29615, United States

  • Prisma Health Cancer Institute - Faris

    ACTIVE_NOT_RECRUITING

    Greenville, South Carolina, 29605, United States

  • Prisma Health Cancer Institute - Greer

    ACTIVE_NOT_RECRUITING

    Greer, South Carolina, 29650, United States

  • Prisma Health Cancer Institute - Seneca

    ACTIVE_NOT_RECRUITING

    Seneca, South Carolina, 29672, United States

  • Prisma Health Cancer Institute - Spartanburg

    ACTIVE_NOT_RECRUITING

    Boiling Springs, South Carolina, 29316, United States

  • ProCure Proton Therapy Center-Somerset

    ACTIVE_NOT_RECRUITING

    Somerset, New Jersey, 08873, United States

  • ProMedica Flower Hospital

    RECRUITING

    Sylvania, Ohio, 43560, United States

    Contact Email: •••••@•••••

  • Queen's Medical Center

    RECRUITING

    Honolulu, Hawaii, 96813, United States

  • Regions Hospital

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • Riverton Hospital

    RECRUITING

    Riverton, Utah, 84065, United States

    Contact Email: •••••@•••••

  • Robert Wood Johnson University Hospital Somerset

    ACTIVE_NOT_RECRUITING

    Somerville, New Jersey, 08876, United States

  • Rohnert Park Cancer Center

    RECRUITING

    Rohnert Park, California, 94928, United States

  • Rush MD Anderson Cancer Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Email: •••••@•••••

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

  • Rutgers New Jersey Medical School

    SUSPENDED

    Newark, New Jersey, 07101, United States

  • Saint Joseph's Hospital and Medical Center

    SUSPENDED

    Phoenix, Arizona, 85013, United States

  • Saint Luke's University Hospital-Bethlehem Campus

    ACTIVE_NOT_RECRUITING

    Bethlehem, Pennsylvania, 18015, United States

  • Saitama Medical University International Medical Center

    RECRUITING

    Saitama, 350-1298, Japan

  • Siteman Cancer Center at Saint Peters Hospital

    RECRUITING

    City of Saint Peters, Missouri, 63376, United States

    Contact Email: •••••@•••••

  • Siteman Cancer Center at West County Hospital

    RECRUITING

    Creve Coeur, Missouri, 63141, United States

    Contact Email: •••••@•••••

  • Siteman Cancer Center-South County

    RECRUITING

    St Louis, Missouri, 63129, United States

    Contact Email: •••••@•••••

  • Smilow Cancer Hospital Care Center-Trumbull

    RECRUITING

    Trumbull, Connecticut, 06611, United States

    Contact Email: •••••@•••••

  • South Sacramento Cancer Center

    RECRUITING

    Sacramento, California, 95823, United States

  • Stanford Cancer Institute Palo Alto

    ACTIVE_NOT_RECRUITING

    Palo Alto, California, 94304, United States

  • Sutter Cancer Centers Radiation Oncology Services-Auburn

    RECRUITING

    Auburn, California, 95603, United States

    Contact Email: •••••@•••••

  • Sutter Cancer Centers Radiation Oncology Services-Roseville

    RECRUITING

    Roseville, California, 95661, United States

    Contact Email: •••••@•••••

  • Sutter Medical Center Sacramento

    RECRUITING

    Sacramento, California, 95816, United States

    Contact Email: •••••@•••••

  • Sutter Solano Medical Center/Cancer Center

    RECRUITING

    Vallejo, California, 94589, United States

    Contact Email: •••••@•••••

  • Tata Memorial Hospital

    SUSPENDED

    Mumbai, 400 012, India

  • Temple University Hospital

    SUSPENDED

    Philadelphia, Pennsylvania, 19140, United States

  • The Cancer Center of Hawaii-Liliha

    SUSPENDED

    Honolulu, Hawaii, 96817, United States

  • The James Graham Brown Cancer Center at University of Louisville

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • The New York Hospital Medical Center of Queens

    ACTIVE_NOT_RECRUITING

    Flushing, New York, 11355, United States

  • The Permanente Medical Group-Roseville Radiation Oncology

    RECRUITING

    Roseville, California, 95678, United States

  • The Research Institute of the McGill University Health Centre (MUHC)

    SUSPENDED

    Montreal, Quebec, H3H 2R9, Canada

  • Thomas Jefferson University Hospital

    ACTIVE_NOT_RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • TidalHealth Nanticoke / Allen Cancer Center

    ACTIVE_NOT_RECRUITING

    Seaford, Delaware, 19973, United States

  • Trinity Health Grand Rapids Hospital

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor

    SUSPENDED

    Ann Arbor, Michigan, 48106, United States

  • Trinity Health Saint Mary Mercy Livonia Hospital

    SUSPENDED

    Livonia, Michigan, 48154, United States

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

  • UC Irvine Health/Chao Family Comprehensive Cancer Center

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

  • UH Seidman Cancer Center at Lake Health Mentor Campus

    RECRUITING

    Mentor, Ohio, 44060, United States

    Contact Email: •••••@•••••

  • UHHS-Westlake Medical Center

    ACTIVE_NOT_RECRUITING

    Westlake, Ohio, 44145, United States

  • UM Sylvester Comprehensive Cancer Center at Coral Gables

    RECRUITING

    Coral Gables, Florida, 33146, United States

  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach

    RECRUITING

    Deerfield Beach, Florida, 33442, United States

  • UM Sylvester Comprehensive Cancer Center at Doral

    RECRUITING

    Doral, Florida, 33166, United States

  • UM Sylvester Comprehensive Cancer Center at Plantation

    RECRUITING

    Plantation, Florida, 33324, United States

  • UNC Lineberger Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • USC / Norris Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Los Angeles, California, 90033, United States

  • UT MD Anderson Cancer Center

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • UT Southwestern/Simmons Cancer Center-Dallas

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

  • UW Cancer Center at ProHealth Care

    RECRUITING

    Waukesha, Wisconsin, 53188, United States

  • University Health Network-Princess Margaret Hospital

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Email: •••••@•••••

  • University of Alabama at Birmingham Cancer Center

    ACTIVE_NOT_RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of Arizona Cancer Center-North Campus

    SUSPENDED

    Tucson, Arizona, 85719, United States

  • University of Arizona Cancer Center-Orange Grove Campus

    SUSPENDED

    Tucson, Arizona, 85704, United States

  • University of Illinois

    RECRUITING

    Chicago, Illinois, 60612, United States

  • University of Iowa/Holden Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kansas Cancer Center

    ACTIVE_NOT_RECRUITING

    Kansas City, Kansas, 66160, United States

  • University of Kansas Cancer Center-Overland Park

    ACTIVE_NOT_RECRUITING

    Overland Park, Kansas, 66210, United States

  • University of Kentucky/Markey Cancer Center

    ACTIVE_NOT_RECRUITING

    Lexington, Kentucky, 40536, United States

  • University of Maryland/Greenebaum Cancer Center

    ACTIVE_NOT_RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Michigan Health - West

    RECRUITING

    Wyoming, Michigan, 49519, United States

  • University of Michigan Rogel Cancer Center

    ACTIVE_NOT_RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Mississippi Medical Center

    ACTIVE_NOT_RECRUITING

    Jackson, Mississippi, 39216, United States

  • University of Nebraska Medical Center

    ACTIVE_NOT_RECRUITING

    Omaha, Nebraska, 68198, United States

  • University of New Mexico Cancer Center

    RECRUITING

    Albuquerque, New Mexico, 87106, United States

  • University of Oklahoma Health Sciences Center

    SUSPENDED

    Oklahoma City, Oklahoma, 73104, United States

  • University of Rochester

    ACTIVE_NOT_RECRUITING

    Rochester, New York, 14642, United States

  • University of Texas Health Science Center at San Antonio

    ACTIVE_NOT_RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Washington Medical Center - Montlake

    ACTIVE_NOT_RECRUITING

    Seattle, Washington, 98195, United States

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

    RECRUITING

    Madison, Wisconsin, 53718, United States

    Contact Email: •••••@•••••

  • University of Wisconsin Carbone Cancer Center - University Hospital

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact Email: •••••@•••••

  • UofL Health Medical Center Northeast

    RECRUITING

    Louisville, Kentucky, 40245, United States

    Contact Email: •••••@•••••

  • Utah Valley Regional Medical Center

    RECRUITING

    Provo, Utah, 84604, United States

    Contact Email: •••••@•••••

  • VCU Massey Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Richmond, Virginia, 23298, United States

  • Vanderbilt University/Ingram Cancer Center

    ACTIVE_NOT_RECRUITING

    Nashville, Tennessee, 37232, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

  • Westchester Medical Center

    SUSPENDED

    Valhalla, New York, 10595, United States

  • Yale University

    ACTIVE_NOT_RECRUITING

    New Haven, Connecticut, 06520, United States

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