Radioactive drug lutathera tested against Hard-to-Treat meningioma

NCT ID NCT06955169

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether the radioactive drug Lutathera can slow or stop the growth of progressive meningioma, a type of brain tumor. About 153 adults with grade 1-3 meningioma will be randomly assigned to receive Lutathera or standard treatments like bevacizumab or everolimus. The study is currently suspended, and researchers are measuring how long participants live without their disease getting worse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lutathera (177Lu-DOTATATE)

What this could lead to

If successful, this could offer a new treatment option for people with progressive meningioma that has not responded to standard therapies.

What could go wrong

This is an early-phase (Phase 2) trial with a small number of participants. The study is currently suspended, and it is unknown if Lutathera will prove more effective than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intracranial meningioma meningioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baptist Health Medical Group Oncology

    Miami, Florida, 33176, United States

  • Baptist MD Anderson Cancer Center

    Jacksonville, Florida, 32207, United States

  • Dana-Farber/Harvard Cancer Center

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 22708, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • NYU Lagone Health

    New York, New York, 10016, United States

  • Piedmont Healthcare

    Atlanta, Georgia, 30318, United States

  • University of California San Diego - Moores Cancer Center

    La Jolla, California, 92093, United States

  • University of California, Irvine

    Irvine, California, 92697, United States

  • University of Miami

    Miami, Florida, 33146, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • Yale University

    New Haven, Connecticut, 06520, United States