New malaria vaccine trial aims to protect women and their future babies
NCT ID NCT06080243
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests the R21/Matrix-M1 malaria vaccine in 330 healthy women aged 18–35 in Mali who may become pregnant. Participants receive two or three doses of the vaccine or a placebo, and are followed for two years to check safety, immune response, and protection against malaria. Pregnant women and their babies are also monitored for safety and infection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
R21/Matrix-M1 malaria vaccine
What this could lead to
If successful, this vaccine could help protect women of childbearing age from malaria, reducing infection and improving maternal and child health in malaria-endemic regions.
What could go wrong
This is a phase II trial with only 330 participants, so results may not apply to larger populations. The vaccine may not provide lasting protection or could have side effects not yet seen.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Koumantou Study Clinic
Bougouni, Sikasso, Mali