Can a common plant compound help rare telomere disease?

NCT ID NCT07628972

Recruiting now Symptom relief Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether quercetin, a natural antioxidant found in many plants, is safe for people with Dyskeratosis congenita or telomere biology disorders. Twelve participants will take quercetin for 24 weeks while researchers monitor side effects and how well people stick with the treatment. The goal is to see if it is safe and feasible to use, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: quercetin (a natural antioxidant found in plants)
What this could lead to: If it works, this could point toward a safe way to manage symptoms of Dyskeratosis congenita or telomere biology disorders.
What could go wrong: This is a very early, small Phase 1 trial with only 12 people. It is designed mainly to check safety, not effectiveness, so it may not lead to a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dyskeratosis congenita telomere syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSKERATOSIS CONGENITA TELOMERE DISEASE

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States

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