New gene therapy combo aims to keep advanced lung cancer in check
NCT ID NCT05703971
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new gene therapy (quaratusugene ozeplasmid) plus an immunotherapy drug (atezolizumab) as maintenance treatment for people with extensive stage small cell lung cancer. The goal is to see if the combination can keep the cancer from growing longer than standard care. About 62 adults who have already responded to initial chemo-immunotherapy will take part. The trial has two phases: first finding the best dose, then checking safety and effectiveness.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Gabrail Cancer Center Research
RECRUITINGCanton, Ohio, 44718, United States
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Northwest Cancer Specialists, P.C.
RECRUITINGPortland, Oregon, 97213-2982, United States
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Northwest Cancer Specialists, P.C.
RECRUITINGPortland, Oregon, 97227, United States
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Northwest Cancer Specialists, P.C.
RECRUITINGTigard, Oregon, 97223, United States
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Northwest Cancer Specialists, P.C.
TERMINATEDVancouver, Washington, 98684, United States
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Oncology_Hematology Care Clinical Trials, LLC
RECRUITINGCincinnati, Ohio, 45211, United States
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Oncology_Hematology Care Clinical Trials, LLC
RECRUITINGCincinnati, Ohio, 45236, United States
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Oncology_Hematology Care Clinical Trials, LLC
RECRUITINGCincinnati, Ohio, 45242, United States
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Oncology_Hematology Care Clinical Trials, LLC
RECRUITINGCincinnati, Ohio, 45245, United States
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Oncology_Hematology Care Clinical Trials, LLC
RECRUITINGFairfield, Ohio, 45014, United States
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Providence Cancer Institute
RECRUITINGPortland, Oregon, 97213, United States
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Rocky Mountain Cancer Centers, LLP
RECRUITINGLone Tree, Colorado, 80124, United States
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Texas Oncology - DFW
RECRUITINGDallas, Texas, 75246, United States
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Texas Oncology - Northeast Texas
RECRUITINGTyler, Texas, 75702, United States
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Virginia Cancer Specialists, PC
RECRUITINGFairfax, Virginia, 22031, United States
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Washington University School of Medicine - Siteman Cancer Center
RECRUITINGSt Louis, Missouri, 63110, United States
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Willamette Valley Cancer Institute (Oregon)
RECRUITINGEugene, Oregon, 97401, United States
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