Engineered immune cells take aim at tough lung cancer
NCT ID NCT05680922
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new treatment called LB2102, which uses a patient's own immune cells (T-cells) that are modified in a lab to recognize and attack DLL3, a protein found on certain lung cancer cells. The study includes about 41 adults with advanced small cell lung cancer or large cell neuroendocrine lung cancer who have already tried standard treatments. The main goal is to find a safe dose and check for side effects, while also seeing if the treatment can shrink tumors.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10017, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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University of Kentucky - Markey Cancer Center
Lexington, Kentucky, 40536, United States