New kidney drug QRX-3 shows promise in slowing disease progression

NCT ID NCT06948292

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed Phase 2 trial tested QRX-3, a drug that boosts NAD activity in kidney cells to reduce damage and improve function. 127 adults with chronic kidney disease stages 3-5 took part over 12 months. Researchers measured changes in kidney function and protein levels in urine to see if QRX-3 slows disease worsening compared to no treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QRX-3

What this could lead to

If successful, QRX-3 could offer a new way to slow kidney function decline in chronic kidney disease patients, potentially delaying the need for dialysis or transplant.

What could go wrong

This is a Phase 2 trial with 127 participants, so results are preliminary. The drug may not show significant benefit over placebo, and long-term safety is not yet established.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease diabetic kidney disease hypertensive nephropathy proteinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Neukidney Inc

    Pasedena, Texas, 77504, United States