New asthma pill shows promise in large trial

NCT ID NCT03215758

Completed Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a daily pill called QAW039 can help people with uncontrolled asthma breathe better. 675 adults and teens took either the drug or a placebo for 12 weeks, on top of their usual inhalers. The main goal was to see if lung function improved.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QAW039 (a drug taken once daily by mouth)

What this could lead to

If it works, this could offer a new add-on treatment option for people whose asthma is not well controlled with current inhalers.

What could go wrong

This is a completed Phase 3 trial, but results are not yet widely known. The drug may not improve lung function enough to be approved, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

Novartis Investigative Site

Flagstaff, Arizona, 86001, United States
Novartis Investigative Site

Phoenix, Arizona, 85006, United States
Novartis Investigative Site

Huntington Beach, California, 92647, United States
Novartis Investigative Site

Long Beach, California, 90808, United States
Novartis Investigative Site

Los Angeles, California, 90025, United States
Novartis Investigative Site

Mission Viejo, California, 92691, United States
Novartis Investigative Site

Mountain View, California, 94040, United States
Novartis Investigative Site

Orange, California, 92868, United States
Novartis Investigative Site

Roseville, California, 95661, United States
Novartis Investigative Site

Walnut Creek, California, 94598, United States
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Denver, Colorado, 80206, United States
Novartis Investigative Site

Tamarac, Florida, 33321, United States
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Winter Park, Florida, 32789, United States
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Albany, Georgia, 31707, United States
Novartis Investigative Site

Dacula, Georgia, 30019, United States
Novartis Investigative Site

Honolulu, Hawaii, 96814, United States
Novartis Investigative Site

Lihue, Hawaii, 96766, United States
Novartis Investigative Site

Overland Park, Kansas, 66210, United States
Novartis Investigative Site

Louisville, Kentucky, 40215, United States
Novartis Investigative Site

Columbia, Missouri, 65203, United States
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Rolla, Missouri, 65401, United States
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Missoula, Montana, 59808, United States
Novartis Investigative Site

Bellevue, Nebraska, 68123, United States
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La Vista, Nebraska, 68128, United States
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Skillman, New Jersey, 08558, United States
Novartis Investigative Site

Asheville, North Carolina, 28801, United States
Novartis Investigative Site

Gastonia, North Carolina, 28054, United States
Novartis Investigative Site

High Point, North Carolina, 27262, United States
Novartis Investigative Site

Cincinnati, Ohio, 45231, United States
Novartis Investigative Site

Edmond, Oklahoma, 73034, United States
Novartis Investigative Site

Eugene, Oregon, 97401-4043, United States
Novartis Investigative Site

Medford, Oregon, 97504, United States
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Portland, Oregon, 97213, United States
Novartis Investigative Site

Portland, Oregon, 97220, United States
Novartis Investigative Site

Rapid City, South Dakota, 57701, United States
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Boerne, Texas, 78006, United States
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Dallas, Texas, 75231, United States
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El Paso, Texas, 79903, United States
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Fort Worth, Texas, 76109, United States
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McKinney, Texas, 75069, United States
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Seattle, Washington, 98122-4379, United States
Novartis Investigative Site

Greenfield, Wisconsin, 53228, United States
Novartis Investigative Site

Berazategui, Buenos Aires, 1888, Argentina
Novartis Investigative Site

CABA, Buenos Aires, C1056ABJ, Argentina
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CABA, Buenos Aires, C1122AAK, Argentina
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CABA, Buenos Aires, C1425BEN, Argentina
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CABA, Buenos Aires, C1426ABP, Argentina
Novartis Investigative Site

Lanus, Buenos Aires, B8000XAV, Argentina
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Mar del Plata, Buenos Aires, 7600, Argentina
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Santa Rosa, La Pampa Province, 6300, Argentina
Novartis Investigative Site

Buenos Aires, Nueve De Julio, B6500BWQ, Argentina
Novartis Investigative Site

Santa Fe, Rosario, S2000DBS, Argentina
Novartis Investigative Site

Rosario, Santa Fe Province, S2000BRH, Argentina
Novartis Investigative Site

Rosario, Santa Fe Province, S2000JKR, Argentina
Novartis Investigative Site

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Novartis Investigative Site

San Miguel de Tucumán, Tucumán Province, T4000IFL, Argentina
Novartis Investigative Site

Buenos Aires, C1012AAR, Argentina
Novartis Investigative Site

Buenos Aires, C1125ABE, Argentina
Novartis Investigative Site

Córdoba, X5003DCE, Argentina
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Mendoza, 5500, Argentina
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Mendoza, M5500CBA, Argentina
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Salta, 4000, Argentina
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Peine, Lower Saxony, 31224, Germany
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Cottbus, Saxony, 03050, Germany
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Aschaffenburg, 63739, Germany
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Bamberg, 96049, Germany
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Berlin, 12157, Germany
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Berlin, 12203, Germany
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Fürstenwalde, 15517, Germany
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Gauting, 82131, Germany
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Leipzig, 04275, Germany
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Lübeck, 23552, Germany
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Prien A Chiemsee, 83209, Germany
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Rüdersdorf, 15562, Germany
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Schleswig, 24837, Germany
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Schwerin, 19055, Germany
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Witten, 58452, Germany
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Budaörs, HUN, 2040, Hungary
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Ajka, 8400, Hungary
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Budapest, 1125, Hungary
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Debrecen, 4032, Hungary
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Gödöllő, 2100, Hungary
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Szeged, 6722, Hungary
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Culiacán, Sinaloa, 80230, Mexico
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Río de Janeiro, 06700, Mexico
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Lipa City, Batangas, 4217, Philippines
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Quezon City, Manila, 1100, Philippines
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Iloilo City, 5000, Philippines
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Manila, 1000, Philippines
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Riyadh, SAU, 11525, Saudi Arabia
Novartis Investigative Site

Jeddah, 21423, Saudi Arabia
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Bardejov, Slovak Republic, 085 01, Slovakia
Novartis Investigative Site

Kežmarok, 060 01, Slovakia
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Michalovce, 071 01, Slovakia
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Poprad, 058 01, Slovakia
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Prešov, 080 01, Slovakia
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Spišská Nová Ves, 052 01, Slovakia
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Žilina, 01207, Slovakia
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Tygerberg, Cape Town, 7505, South Africa
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Cape Town, 7500, South Africa
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Chatsworth, 4092, South Africa
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Durban, 4001, South Africa
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Pretoria, 0183, South Africa
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Istanbul, TUR, 34098, Turkey (Türkiye)
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Adana, 01330, Turkey (Türkiye)
Novartis Investigative Site

Ankara, 06100, Turkey (Türkiye)
Novartis Investigative Site

Istanbul, 34020, Turkey (Türkiye)
Novartis Investigative Site

Mersin, 33343, Turkey (Türkiye)
Novartis Investigative Site

Talas / Kayseri, 38039, Turkey (Türkiye)
Novartis Investigative Site

Yenisehir/Izmir, 35110, Turkey (Türkiye)