New vaccine combo aims to stop breast cancer return

NCT ID NCT02826434

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This early-phase study tests a cancer vaccine (PVX-410) alone or with an immunotherapy drug (durvalumab) in 22 people with stage II or III triple negative breast cancer who have completed standard treatment. The goal is to see if the vaccine is safe and can boost the immune system to help prevent the cancer from coming back. Participants must have a specific immune type (HLA-A2+).

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33607, United States

  • Massachusetts general Hospital

    Boston, Massachusetts, 02114, United States

  • New York University School of Medicine

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.