New combo therapy aims to shrink lung tumors after first treatment fails

NCT ID NCT06841055

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tests a new drug called pumitamig combined with standard chemotherapy for people with advanced non-small cell lung cancer whose disease worsened after initial treatment. About 60 participants will receive the combination to see if it is safe and helps shrink tumors. The goal is to find a better option for controlling the cancer when first-line therapy stops working.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Ankara Bilkent City Hospital
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Baptist Health Hardin
RECRUITING

Elizabethtown, Kentucky, 42701, United States
Baskent University Adana Turgut Noyan Application and Research Center Kisla Health Campus
RECRUITING

Adana, 01250, Turkey (Türkiye)
Cancer Research SA (CRSA)
RECRUITING

Adelaide, South Austraila, 5000, Australia
Chungbuk National University Hospital
RECRUITING

Cheongju-si, 28644, South Korea
Gachon University Gil Medical Center
RECRUITING

Incheon, 21565, South Korea
Gyeongsang National University Hospital (GNUH)
RECRUITING

Jinju, Gyeongsangnam-do, 52727, South Korea
Hobart Hospital-Royal Hobart Hospital
RECRUITING

Hobart, Tasmania, 7000, Australia
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain
Institut dInvestigacio Biomedica de Bellvitge (IDIBELL)
RECRUITING

Barcelona, 08908, Spain
Koc Universitesi Hastanesi (Koc University Hospital)
RECRUITING

Zeytinburnu, 34010, Turkey (Türkiye)
Liverpool Cancer Therapy Centre
RECRUITING

Liverpool, New South Wales, 2170, Australia
Memorial Ankara Hospital
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Memorial Antalya Hospital
RECRUITING

Antalya, 07090, Turkey (Türkiye)
Metro South Health - Princess Alexandra Hospital (PAH)
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
NYU Langone - NYU Grossman School of Medicine
RECRUITING

New York, New York, 10016, United States
One Clinical Research - Hollywood Private Hospital
RECRUITING

Nedlands, Western Australia, 6009, Australia
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Sarah Cannon Research Institute
RECRUITING

London, W1G 6AD, United Kingdom
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
St James's University Hospital - Leeds Teaching Hospitals NHS Trust
RECRUITING

Leeds, LS9 7TF, United Kingdom
Texas Oncology, P.A.
COMPLETED

Houston, Texas, 77090, United States
The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The University of Alabama at Birmingham Hospital
RECRUITING

Birmingham, Alabama, 35249, United States
Universitat de Valencia - Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulevar Sur)
RECRUITING

Valencia, 46026, Spain
Velindre NHS Trust, Velindre Cancer Centre
RECRUITING

Cardiff, CF14 2TL, United Kingdom
Yeditepe University Hospital
RECRUITING

Istanbul, 34752, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER