Zapping polyps away: electric pulses could replace surgery

NCT ID NCT06317727

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing a new device that uses small electric pulses to destroy colon polyps during a colonoscopy. Researchers want to see if it is safe and effective for removing polyps. Thirty adults with at least one polyp larger than 5mm in the lower colon will be enrolled. The main goal is to check for side effects like bleeding or pain, and to see if polyps come back.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Irreversible electroporation via EndoVE device and ePORE generator
What this could lead to
If successful, this could offer a new, less invasive way to remove colon polyps during a routine colonoscopy.
What could go wrong
This is a very early pilot study with only 30 people, so results may not apply to everyone. Risks include bleeding, pain, or bowel perforation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • King's College Hospital

    RECRUITING

    London, SE5 9RS, United Kingdom

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Other studies related to the condition(s) this trial covers.