Zapping polyps away: electric pulses could replace surgery

NCT ID NCT06317727

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new device that uses small electric pulses to destroy colon polyps during a colonoscopy. Researchers want to see if it is safe and effective for removing polyps. Thirty adults with at least one polyp larger than 5mm in the lower colon will be enrolled. The main goal is to check for side effects like bleeding or pain, and to see if polyps come back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Irreversible electroporation via EndoVE device and ePORE generator

What this could lead to

If successful, this could offer a new, less invasive way to remove colon polyps during a routine colonoscopy.

What could go wrong

This is a very early pilot study with only 30 people, so results may not apply to everyone. Risks include bleeding, pain, or bowel perforation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • King's College Hospital

    RECRUITING

    London, SE5 9RS, United Kingdom