Pause-and-Flush: could a simple change prevent dialysis catheter blockages?
NCT ID NCT07567456
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a pulsatile flushing technique—giving saline in small bursts with short pauses—can reduce blockages in tunnelled central venous catheters used for haemodialysis. About 591 patients across 14 renal centres in Hong Kong will be assigned to one of two pause intervals (0.4 or 1 second) or standard flushing. The goal is to find the best way to maintain catheter function and improve patient outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pulsatile flushing technique (a catheter care procedure using intermittent saline boluses with pauses)
- What this could lead to
- If it works, this could establish a better way to keep dialysis catheters clear, reducing blockages and improving treatment for kidney patients.
- What could go wrong
- This is a non-randomized trial, so results may be less reliable. The technique is compared to standard flushing, and the best pause interval is unknown. It may not work better than current practice.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Queen Elizabeth Hospital
RECRUITINGKowloon, Hong Kong
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