Veterans' PTSD study seeks best treatment match
NCT ID NCT04961190
First seen Jan 09, 2026 · Last updated May 06, 2026 · Updated 18 times
Summary
This study compares three approaches for treating PTSD in military veterans: talk therapy (Prolonged Exposure), antidepressant medication (paroxetine or venlafaxine), or both together. About 300 veterans from six VA medical centers will be randomly assigned to one of these treatments for 14 weeks, with follow-ups up to 40 weeks. The goal is to see which treatment works best overall and to develop a tool that predicts the best option for each person.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Birmingham VA Healthcare System
Birmingham, Alabama, 35233, United States
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Coatesville VA Medicial Center
Coatesville, Pennsylvania, 19320, United States
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Corporal Michael J. Crescenz VA Medical Center
Philadelphia, Pennsylvania, 19104, United States
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Milwaukee VA Medical Center
Milwaukee, Wisconsin, 53295, United States
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VA North Texas Healthcare System
Dallas, Texas, 75216, United States
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VA Palo Alto Healthcare System
Menlo Park, California, 94025, United States
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VA San Diego Healthcare System
San Diego, California, 92161, United States
Conditions
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