Could your genes raise Baby's risk from common painkillers?
NCT ID NCT00710177
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is investigating whether natural differences in the PTGS1 gene make some newborns more likely to develop a serious lung condition called persistent pulmonary hypertension (PPHN) after their mothers took over-the-counter pain relievers (NSAIDs) during pregnancy. Researchers will compare 200 infants—some with PPHN and some healthy—to see if genetic variations play a role. The goal is to better understand why some babies are affected, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify newborns at higher risk for PPHN after NSAID exposure, potentially guiding safer medication use during pregnancy.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find a clear genetic link, and results may not change current medical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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