Could your genes raise Baby's risk from common painkillers?
NCT ID NCT00710177
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is investigating whether natural differences in the PTGS1 gene make some newborns more likely to develop a serious lung condition called persistent pulmonary hypertension (PPHN) after their mothers took over-the-counter pain relievers (NSAIDs) during pregnancy. Researchers will compare 200 infants—some with PPHN and some healthy—to see if genetic variations play a role. The goal is to better understand why some babies are affected, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify newborns at higher risk for PPHN after NSAID exposure, potentially guiding safer medication use during pregnancy.
What could go wrong
This is an observational study, not a treatment trial. It may not find a clear genetic link, and results may not change current medical practice.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact