Can we predict psychosis? massive global study seeks answers
NCT ID NCT05905003
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times
Summary
This observational study is gathering data from over 2,600 young people (ages 12-30) who are at clinical high risk for psychosis, plus healthy volunteers, across 13 countries. Researchers are using clinical assessments, cognitive tests, and biomarkers to develop computer algorithms that can predict whether someone will recover, develop psychosis, or have ongoing symptoms. The goal is to better identify who needs early treatment and to speed up testing of new medications.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02115, United States
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Copenhagen Research Center for Mental Health (CORE)
Copenhagen, DK-2900, Denmark
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Department of Psychiatry, Chonnam National University Hospital & Mindlink
Gwangju, 61469, South Korea
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Early Psychosis Intervention Programme (EPIP) Clinic, Institute of Mental Health
Singapore, 539747, Singapore
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Forward Thinking Birmingham
Birmingham, B4 6DF, United Kingdom
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HEP and co-located Headspace Adelaide
Adelaide, South Australia, 5000, Australia
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Hartford Healthcare
Hartford, Connecticut, 06106, United States
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Headspace Melton
Melton South, Victoria, 3338, Australia
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Headspace, Craigieburn
Craigieburn, Victoria, 3064, Australia
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Headspace, Glenroy
Glenroy, Victoria, 3046, Australia
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Headspace, Sunshine
Sunshine, Victoria, 3020, Australia
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Headspace, Werribee
Werribee, Victoria, 3030, Australia
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Hospital Clínico Universidad de Chile (HCUCH)
Santiago, Santiago Metropolitan, 8380456, Chile
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Instituto de Psiquiatría y Salud Mental Hospital General Universitario Gregorio Marañón
Madrid, Spain
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King's College London
London, SE5 8AF, United Kingdom
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Klinik für Psychiatrie und Psychotherapie, University of Cologne
Cologne, Brescia, 50931, Germany
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Ludwig-Maximilians-Universität Munich
Munich, Germany
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McGill University
Montreal, Quebec, H4H 1R3, Canada
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Northwell Health
Queens, New York, 11004, United States
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Northwestern University
Evanston, Illinois, 60201, United States
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Orygen Specialist Programs, Melbourne
Parkville, Victoria, 3122, Australia
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Seoul National University College of Medicine
Seoul, 03082, South Korea
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Shanghai Jiao Tong University
Shanghai, 200030, China
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Temple University
Philadelphia, Pennsylvania, 19122, United States
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The University Hospital Jena, Department of Psychiatry
Jena, Thuringia, 07743, Germany
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The University of Hong Kong, Department of Psychiatry
Hong Kong, Hong Kong
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Treatment and Early Intervention in Psychosis Program (TIPP) & Center for Psychiatric Neuroscience (CNP), Department of Psychiatry, Lausanne University Hospital
Lausanne, 1008, Switzerland
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University of Calgary
Calgary, Alberta, Canada
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University of California Irvine
Irvine, California, 92697, United States
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University of California Los Angeles
Los Angeles, California, 90095,, United States
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University of California San Diego
San Diego, California, 92103, United States
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University of California San Francisco
San Francisco, California, 94121, United States
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University of Cambridge
Cambridge, CB4 1PR, United Kingdom
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University of Georgia
Athens, Georgia, 30602, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Oregon
Eugene, Oregon, 97401, United States
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University of Pavia
Pavia, Pavia, 27100, Italy
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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Washington University
St Louis, Missouri, 63110, United States
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Yale University/Connecticut Mental Health Center
New Haven, Connecticut, 06519, United States
Conditions
Explore the condition pages connected to this study.