New hope for PSP: experimental drug LM11A-31 enters key trial
NCT ID NCT07264283
First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times
Summary
This Phase 2 trial tests whether the drug LM11A-31 can slow the progression of Progressive Supranuclear Palsy (PSP), a rare brain disorder that affects movement and balance. About 147 people with early-stage PSP will receive either the drug or a placebo twice daily for several months. Researchers will measure changes in disease severity using a specialized rating scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LM11A-31
- What this could lead to
- If successful, this could point toward a treatment that slows the worsening of PSP symptoms.
- What could go wrong
- This is an early Phase 2 trial with only 147 participants, so results may not confirm benefit. The drug may not slow disease progression or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco (UCSF), Memory and Aging Center
San Francisco, California, 94158, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.