Magic mushroom therapy gets a monitor: new trial for stubborn depression

NCT ID NCT07211438

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tests whether having a trained monitor during psilocybin (magic mushroom) therapy helps adults with depression that hasn't improved with other treatments. About 40 people will receive the therapy and be followed to see if it's safe and helpful. The goal is to reduce depression symptoms and improve well-being.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M6J1H4, Canada

  • Toronto Western Hospital (University Health Network)

    RECRUITING

    Toronto, Ontario, M5T 2S8, Canada

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