Magic mushroom compound tested as opioid addiction aid

NCT ID NCT04161066

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 20 times

Summary

This early-stage study tests whether adding psilocybin (the active ingredient in magic mushrooms) to standard buprenorphine/naloxone treatment is safe for people with opioid use disorder. Ten adults on stable medication will receive two doses of psilocybin while being monitored for side effects, withdrawal, and cravings. The goal is to see if psilocybin can help improve treatment outcomes without causing harm.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Wisconsin

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact

Conditions

Explore the condition pages connected to this study.