Magic mushrooms meet opioid treatment: a safety check

NCT ID NCT04161066

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 27 times

Summary

This early-stage study tests whether adding two doses of psilocybin (the active ingredient in magic mushrooms) to standard buprenorphine/naloxone treatment is safe for adults with opioid use disorder. Ten participants will be closely monitored for side effects and changes in withdrawal symptoms, cravings, and quality of life. The goal is to see if psilocybin can safely support recovery without causing harm.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Wisconsin

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact

Conditions

Explore the condition pages connected to this study.