Magic mushroom compound tested for Cancer-Related depression

NCT ID NCT05947383

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether up to two doses of psilocybin (the active ingredient in magic mushrooms) can safely reduce depression in adults who have both cancer and major depressive disorder. About 56 participants will receive either psilocybin or a placebo in a first session, and those who don't improve can receive psilocybin in a second open-label session. The goal is to see if this approach eases depressive symptoms better than a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer Depression major depressive disorder neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sunstone Medical, PC

    Rockville, Maryland, 20850, United States