Magic mushroom compound tested as cannabis addiction treatment
NCT ID NCT06660381
First seen Jun 25, 2026 · Last updated Jun 25, 2026
Summary
This pilot study at Johns Hopkins University is testing whether psilocybin, the active ingredient in magic mushrooms, can help people with cannabis use disorder. Twelve adults will receive two doses of psilocybin along with counseling over 12 weeks. Researchers will track cannabis use and related symptoms for up to 6 months after treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins Center for Psychedelic and Consciousness Research
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If this works, it could point toward a new treatment option for cannabis use disorder, helping people reduce or stop their cannabis use.
What could go wrong
This is a very small, early-phase pilot study with only 12 people and no placebo group. The results may not apply to everyone, and psilocybin can cause intense psychological effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.