Magic mushroom compound tested as cannabis addiction treatment

NCT ID NCT06660381

Recruiting now Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Nov 17, 2025 · Last updated Apr 24, 2026 · Updated 15 times

Summary

This early study tests whether psilocybin, the active ingredient in magic mushrooms, can help people with cannabis use disorder cut back or stop using cannabis. Twelve adults will receive two psilocybin sessions with psychological support over 12 weeks, and their cannabis use will be tracked via self-reports and urine tests. The goal is to see if this approach is safe and promising enough for larger studies.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Johns Hopkins Center for Psychedelic and Consciousness Research
RECRUITING

Baltimore, Maryland, 21224, United States

Contact Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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CANNABIS USE DISORDER