Magic mushroom compound tested to restore joy in depressed patients
NCT ID NCT07490353
First seen Apr 18, 2026 · Last updated May 01, 2026 · Updated 3 times
Summary
This early-stage study explores whether psilocybin, the active ingredient in magic mushrooms, can reduce anhedonia (loss of pleasure) in people with major depression. 85 participants, including healthy volunteers, will receive psilocybin in two sessions—one with a drug that blocks the psychedelic effects. Brain scans and questionnaires will measure changes in reward processing, well-being, and mood. The goal is to understand how the psychedelic experience itself contributes to any anti-anhedonic benefits.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Medical University of Vienna, Department of Psychiatry and Psychotherapy, Division of General Psychiatry
RECRUITINGVienna, State of Vienna, 1160, Austria
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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