Magic mushroom compound tested for brain boost in seniors
NCT ID NCT06367738
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-stage study is looking at how a single dose of psilocybin, the active ingredient in magic mushrooms, might affect brain structure and function in healthy older adults aged 60 to 85. Researchers will use MRI scans to measure changes in brain plasticity and activity. The goal is to understand whether psilocybin can promote brain flexibility in aging, but this is a small, exploratory trial with no direct treatment aim.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If successful, this could reveal how psilocybin promotes brain flexibility in aging, potentially pointing toward future therapies for age-related cognitive decline.
What could go wrong
This is a very early Phase 1 study with only 40 healthy participants, so results may not apply to the general population or lead to any treatment. The doses vary widely, and the study focuses on brain imaging changes, not clinical benefits.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, Berkeley
RECRUITINGBerkeley, California, 94720, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••