Brain scans reveal Psilocybin's effects on depression

NCT ID NCT06072898

First seen Apr 06, 2026 · Last updated Apr 25, 2026 · Updated 1 time

Summary

This study uses brain scans to see how psilocybin (the active ingredient in magic mushrooms) changes brain activity in people with depression. Fifty adults with major depression will receive either psilocybin or a placebo during two treatment sessions, with MRI scans taken right after. The goal is to understand which brain changes are specific to psilocybin, not to test it as a treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N3M5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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