Magic mushroom therapy shows promise for depression in small trial
NCT ID NCT05227612
First seen Dec 29, 2025 · Last updated May 02, 2026 · Updated 19 times
Summary
This early-stage study tested whether combining psilocybin (the active ingredient in magic mushrooms) with cognitive behavioral therapy is safe and helpful for people with depression. Sixteen adults received two doses of psilocybin along with 12 therapy sessions. The goal was to see if this approach is acceptable to patients and can reduce depressive symptoms.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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UCLA Semel Institute
Los Angeles, California, 90095, United States
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